BST1 Antikörper

Produktnummer ABIN1105911

Dieser Anti-BST1 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von BST1 in FACS. Geeignet für Human.

Kurzübersicht für BST1 Antikörper (ABIN1105911)

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BST1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: RF3

Produktdetails anti-BST1 Antikörper

Spezifität: This antibody reacts with CD157 antigen. This antibody reacts with RASV5-5 cells, and does not react with a healthy donor-derived nonsupportive cell line, NFSV1-1.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein A agarose

Immunogen: RA-derived BM stromal cell line RASV5-5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Prepare a stock solution by dissolving the lyophilized antibody in 100 μL of distilled water. After reconstitution, the IgG concentration will be 1 mg/mL.

Buffer: PBS ( pH 7.2), 0.09 % NaN3, 1 % sucrose

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Details zu BST1

Target: BST1 (Bone Marrow Stromal Cell Antigen 1 (BST1))

Andere Bezeichnung: CD157 / BST1

Hintergrund: In the bone marrow (BM) hematopoietic microenvironment, stromal cells play crucial roles. Stromal cells secrete a variety of cytokines and express cell surface molecules that regulate the growth of hematopoietic cells. BM stromal cell lines derived from patients with rheumatoid arthritis (RA) have augmented ability to support the growth of a murine pre-B cell line, DW34. BST-1 (bone marrow stromal cell antigen-1) is expressed on BM stromal cell lines and is responsible for an augmented ability to support pre-B cell line growth. BST-1 is also expressed by RA-derived synovial cell lines, a myelomonocytic cell lines, and HUVEC, suggesting that BST-1 has other functional roles than just supporting pre-B cell growth.Synonyms: ADP-ribosyl cyclase 2, BST-1, Bone marrow stromal antigen 1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2

Gen-ID: 683

NCBI Accession: NP_004325

UniProt: Q10588